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eFootball PES 2021 SEASON UPDATE (PS4)
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eFootball PES 2021 SEASON UPDATE (PS4)
Season update - PES 2021 is an updated version of last year's title, efootball PES 2020, providing the latest player data and Club rosters. Due to the delayed Season endings for many leagues, the latest data for certain licensed leagues and teams will be available via updates at launch and after (Internet connection required)
Exclusive UEFA Euro 2020 content - ahead of the real-life tournament in 2021, the official UEFA Euro 2020 content will be included at launch in PES 2021. Featuring the offline UEFA Euro 2020 tournament Mode, all 55 UEFA National teams, Wembley Stadium and more, This is the best way to simulate the tournament before and after its Summer debut
Iconic moment series - relive and recreate memorable moments from the careers of current and former football Superstars with this new myClub series
Partner Club editions - For the first time, fans will be able to purchase special Club editions of PES 2021 through digital platforms. Available for FC Barcelona, juventus, Manchester United, FC Bayern and arsenal FC, the all-new Club editions will include exclusive club-specific content such as myClub squads, iconic moment series players, unique kits, branded menus and more
Master League - An immersive single-player mode that puts you in the manager's seat of your Very own football Club, featuring an interactive dialogue system with cinematic cutscenes, realistic transfers and more. As you work to build and develop your very own Club, you'll be charged with driving progression through meaningful choices both on and off the pitch
New Legend managers have been added to master League in PES 2021, with details to be revealed soon
Match day - Stand alongside PES newcomers and seasoned professionals as you work together to take on football's biggest matches in this competitive online mode. Pick your favorite Club and take on other users of the same skill level to contribute to your side's victory. Rack up enough wins and be in with a chance of representing your side in an epic final Showdown
MyClub - A hugely popular online mode where your objective is to create your very own ideal team through signing and testing players, managers and their tactical fit. The more you play, the more game points (GP) you will be rewarded to further improve your team
For those who played myClub in efootball PES 2020, there will be a special loyalty bonus available with various rewards depending on the milestones achieved in-game. Reward and milestone details will be published on the official website
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Product description
Platform:PlayStation 4
Product Description
amp;Graphical enhancements; football PES 2021 season update delivers all the critically acclaimed features and gameplay from efootball PES 2020 that was awarded "best sports game" At E3 2019, plus more. Boasting the latest player and Club data for the new Season, the game also includes the exclusive UEFA Euro 2020 mode and content in advance of the rescheduled real-life tournament.As the PES franchise celebrates its 25th anniversary since its debut in 1995 and over 100 million copies sold, Konami invites football fans all over the world to join us once again as we head out onto the pitch for a new action-packed Season of football and prepare for the future.
Set Contains:
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eFootball PES 2021 SEASON UPDATE (PS4)
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This open-label, single-arm study investigated the long-term efficacy of tafasitamab plus lenalidomide in 81 patients with relapsed/refractory diffuse large B-cell lymphoma. The response rate was 57.5%, including complete responses in 40.0% of patients, and the median duration of response was 43.9 months. This treatment is a valuable option for patients not eligible for autologous stem-cell transplantation.
Grey zone lymphoma is a B-cell lymphoma, unclassifiable, with features intermediate between those of large B-cell lymphoma and classic Hodgkin lymphoma. The in-depth study of the two adolescent patients described in this case report expands the clinicopathological and genomic spectrum of this rare pediatric disease. Moreover, it provides information on their response to treatment.
The clinical picture of 56 patients with congenital amegakaryocytic thrombocytopenia due to MPL mutations was much more varied than previously thought. Twenty-five per cent of them had no signs of thrombocytopenia at birth, and 50% had non-hematologic defects. Pancytopenia developed in (nearly) all patients and hematopoietic stem-cell transplantation was effective in 87% of cases.
Sickle red blood cells exhibit abnormal adhesion to laminin mediated by Lu/BCAM protein at their surface. This study provides evidence of the involvement of oxidative stress in post-translational modifications of Lu/BCAM which impact the protein’s distribution and cis-interaction with glycophorin C at the cell surface activating its adhesive function in dense sickle red cells. The authors speculate that antioxidant drugs might attenuate this phenomenon.